(9R) -Exatecan
(9R) -Exatecan (DX8951f) is the (1R,9S) stereoisomer of Exatecan (HY-13631) . Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
Product Specifications
CAS Number
[2489613-17-2]
Product Name Alternative
(9R) -DX8951f
UNSPSC
12352005
Target
ADC Payload; Drug Derivative; Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
N[C@@H]1C2=C3C(C(N4C3)=CC([C@@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62
Molecular Formula
C24H22FN3O4
Molecular Weight
435.45
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
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