Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Iso-ADP ribose (TEA)

Iso-ADP ribose (isoADPr) TEA is a ligand used for protein nucleic acid modification. iso-ADP ribose TEA is a structure comprising parts of two consecutive ADP-ribosyl units within the PAR chain. iso-ADP ribose TEA is the small-molecule ligand for RING finger protein 146 (RNF146) WWE. A single iso-ADP ribose TEA molecule triggers the activation of RNF146 by interacting with the basic Lys61 residue in the RING domain[1][2].

Product Specifications

UNSPSC

12352005

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Others

Purity

99.97

Smiles

CCN(CC)CC.CCN(CC)CC.NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O[C@H]4[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O4)[C@H](O)[C@@H](COP(O)(O)=O)O3

Molecular Formula

C27H53N7O14P2

Molecular Weight

761.70

References & Citations

[1]Kewen Peng, et al. Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS Chem Biol. 2024 Feb 16;19 (2) :300-307.|[2]Federico Teloni, et al. Readers of poly (ADP-ribose) : designed to be fit for purpose. Nucleic Acids Res. 2016 Feb 18;44 (3) :993-1006.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-135782A/iso-ADP-ribose-TEA-SDS-MedChemExpress.pdf

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Monkey Interleukin 3 ELISA kit
GTR10443376 96 Well

Monkey Interleukin 3 ELISA kit

Ask
View Details
Human IL-1 beta/IL-1F2 Alexa Fluor 488 Antibody
IC201G-100UG 100 µg

Human IL-1 beta/IL-1F2 Alexa Fluor 488 Antibody

Ask
View Details
AY026312 AAV siRNA Pooled Vector
53178164 1.0 μg

AY026312 AAV siRNA Pooled Vector

Ask
View Details
Carsons Formalin 10%
RRFF4002-F 2.5 L

Carsons Formalin 10%

Ask
View Details
Goat Polyclonal NEK7 Antibody
NBP1-68866 0.1 mg

Goat Polyclonal NEK7 Antibody

Ask
View Details
Human RNF135 siRNA
abx904604-01 15 nmol

Human RNF135 siRNA

Ask
View Details