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Penoxsulam

Penoxsulam is an acetolactate synthase (ALS) inhibitor herbicide. Penoxsulam inhibits Candida auris acetohydroxyacid synthase (AHAS) with a Ki value of Candida auris infections[1][2].

Product Specifications

CAS Number

[219714-96-2]

UNSPSC

12352005

Hazard Statement

H410

Target

Acetolactate Synthase (ALS) ; Fungal; Herbicide

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=S(C1=C(C(F)(F)F)C=CC=C1OCC(F)F)(NC2=NN3C(OC)=NC=C(OC)C3=N2)=O

Molecular Formula

C16H14F5N5O5S

Molecular Weight

483.37

Precautions

P273-P391-P501

References & Citations

[1]Agnew-Francis KA, et al. Herbicides That Target Acetohydroxyacid Synthase Are Potent Inhibitors of the Growth of Drug-Resistant Candida auris. ACS Infect Dis. 2020 Nov 13;6 (11) :2901-2912. |[2]Jabusch TW, et al. Partitioning of penoxsulam, a new sulfonamide herbicide. J Agric Food Chem. 2005 Sep 7;53 (18) :7179-83.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

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