Penoxsulam
Penoxsulam is an acetolactate synthase (ALS) inhibitor herbicide. Penoxsulam inhibits Candida auris acetohydroxyacid synthase (AHAS) with a Ki value of Candida auris infections[1][2].
Product Specifications
CAS Number
[219714-96-2]
UNSPSC
12352005
Hazard Statement
H410
Target
Acetolactate Synthase (ALS) ; Fungal; Herbicide
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=S(C1=C(C(F)(F)F)C=CC=C1OCC(F)F)(NC2=NN3C(OC)=NC=C(OC)C3=N2)=O
Molecular Formula
C16H14F5N5O5S
Molecular Weight
483.37
Precautions
P273-P391-P501
References & Citations
[1]Agnew-Francis KA, et al. Herbicides That Target Acetohydroxyacid Synthase Are Potent Inhibitors of the Growth of Drug-Resistant Candida auris. ACS Infect Dis. 2020 Nov 13;6 (11) :2901-2912. |[2]Jabusch TW, et al. Partitioning of penoxsulam, a new sulfonamide herbicide. J Agric Food Chem. 2005 Sep 7;53 (18) :7179-83.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135713/
Scientific Category
Reference compound2
Clinical Information
No Development Reported
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