DHODH-IN-34

DHODH-IN-34 (Compound 21q) is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 value of 13 nM. DHODH-IN-34 is promising for research of RNA viruses such as measles virus and chikungunya virus[1].

Product Specifications

CAS Number

[1644156-93-3]

UNSPSC

12352005

Target

Dihydroorotate Dehydrogenase

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

CCC1=CN=C(N2N=C(OC(C)C)C(OC3=C(F)C=CC=C3F)=C2C)N=C1

Molecular Formula

C19H20F2N4O2

Molecular Weight

374.38

References & Citations

[1]Munier-Lehmann H, et al. Original 2- (3-alkoxy-1H-pyrazol-1-yl) pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH) . J Med Chem. 2015 Jan 22;58 (2) :860-77.