DHODH-IN-34
DHODH-IN-34 (Compound 21q) is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 value of 13 nM. DHODH-IN-34 is promising for research of RNA viruses such as measles virus and chikungunya virus[1].
Product Specifications
CAS Number
[1644156-93-3]
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
CCC1=CN=C(N2N=C(OC(C)C)C(OC3=C(F)C=CC=C3F)=C2C)N=C1
Molecular Formula
C19H20F2N4O2
Molecular Weight
374.38
References & Citations
[1]Munier-Lehmann H, et al. Original 2- (3-alkoxy-1H-pyrazol-1-yl) pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH) . J Med Chem. 2015 Jan 22;58 (2) :860-77.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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