Sclerotioramine

Sclerotioramine (Compound 1), a red pigment, is an antioxidant compound. Sclerotioramine can be isolated from the endolichenic fungus Penicillium sp.-strain 1322P. Sclerotioramine has potent antibacterial activity with MICs of 3.125, 3.125 and 6.25 μg/mL for Bacillus subtilis, Bacillus megaterium and Shigella dysentery, respectively. Sclerotioramine also has significant antifungal activity against Pestalotiopsis theae, Cochliobolus miyabeanus and Exserohilum turcicum[1][2].

Product Specifications

CAS Number

[34695-81-3]

UNSPSC

12352005

Target

Bacterial; Endogenous Metabolite; Fungal

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(C1(OC(C)=O)C)C(Cl)=C2C=C(/C=C/C(C)=C/C(C)CC)NC=C2C1=O

Molecular Formula

C21H24ClNO4

Molecular Weight

389.87

References & Citations

[1]Huang L, et al. Isolation and Characterization of Antimicrobial Metabolites from the Sophora tonkinensis-Associated Fungus Penicillium sp. GDGJ-N37. Molecules. 2024 Jan 10;29 (2) :348. |[2]Kawakami H, et al. Antioxidant compounds produced by endolichenic fungus Penicillium sp.-strain 1322P isolated from Pyxine subcinerea. Arch Microbiol. 2024 Mar 21;206 (4) :187.