Tretazicar (Standard)
Tretazicar (Standard) is the analytical standard of Tretazicar. This product is intended for research and analytical applications. Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD (P) H:quinone oxidoreductase 1 (NQO1) [1][2].
Product Specifications
CAS Number
[21919-05-1]
UNSPSC
12352100
Target
DNA Alkylator/Crosslinker; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
O=C(N)C1=CC(N2CC2)=C([N+]([O-])=O)C=C1[N+]([O-])=O
Molecular Formula
C9H8N4O5
Molecular Weight
252.18
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13543R/
Scientific Category
Reference Standards
Available Sizes
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