(R) -Linezolid-d3

(R) -Linezolid-d3 ((R) -PNU-100766-d3) is the deuterium labeled (R) -Linezolid. (R) -Linezolid is an impurity of Linezolid (PNU-100766) . Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis[1][2].

Product Specifications

CAS Number

[1795786-02-5]

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

O=C1N(C[C@@H](CNC(C([2H])([2H])[2H])=O)O1)C2=CC(F)=C(C=C2)N3CCOCC3

Molecular Formula

C16H17D3FN3O4

Molecular Weight

340.36

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Bednarek E, et al. NMR and molecular modeling study, as complementary techniques to capillary electrophoresis method to elucidate the separation mechanism of linezolid enantiomers. J Chromatogr A. 2008 Jun 6;1193 (1-2) :164-71.|[3]Clemett D, et al. Linezolid. Drugs. 2000 Apr;59 (4) :815-27; discussion 828.