Tetrahydroechinocandin B

Tetrahydroechinocandin B (L 687,901) is a potent antifungal agent. Tetrahydroechinocandin B inhibits 1,3-beta-D-glucan synthesis with an IC50 of 0.85 μg/mL[1].

Product Specifications

CAS Number

[54651-06-8]

Product Name Alternative

L-687901

UNSPSC

12352005

Target

Fungal

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(CCCCCCCCCCCCCCCCC)N[C@H](C(N[C@@]1([H])[C@H](O)C)=O)C[C@H]([C@H](NC([C@@]([C@H]2O)([H])N(C[C@@H]2C)C([C@](NC([C@](NC([C@@](C[C@H]3O)([H])N(C3)C1=O)=O)([H])[C@H](O)[C@H](C(C=C4)=CC=C4O)O)=O)([H])[C@H](O)C)=O)=O)O)O

Molecular Formula

C52H85N7O16

Molecular Weight

1064.27

References & Citations

[1]Bartizal K, et al. In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin. Antimicrob Agents Chemother. 1992 Aug;36 (8) :1648-57.