AE9C90CB

AE9C90CB, muscarinic receptor antagonist, has greater affinity for M3 muscarinic receptors with pKi of 9.90 and was 20-fold more selective for M3 than for M2 muscarinic receptors[1].

Product Specifications

CAS Number

893426-98-7

UNSPSC

12352005

Target

MAChR

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

[H][C@@]1(CNC2)[C@@]2([H])[C@H]1CN(C)C(C(C3=CC=CC=C3)(C4=CC=CC=C4)O)=O.Cl

Molecular Formula

C21H25ClN2O2

Molecular Weight

372.89

References & Citations

[1]S Sinha, et al. AE9C90CB: a novel, bladder-selective muscarinic receptor antagonist for the treatment of overactive bladder. Comparative Study Br J Pharmacol. 2010 Jul;160 (5) :1119-27.