AE9C90CB
AE9C90CB, muscarinic receptor antagonist, has greater affinity for M3 muscarinic receptors with pKi of 9.90 and was 20-fold more selective for M3 than for M2 muscarinic receptors[1].
Product Specifications
CAS Number
893426-98-7
UNSPSC
12352005
Target
MAChR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
[H][C@@]1(CNC2)[C@@]2([H])[C@H]1CN(C)C(C(C3=CC=CC=C3)(C4=CC=CC=C4)O)=O.Cl
Molecular Formula
C21H25ClN2O2
Molecular Weight
372.89
References & Citations
[1]S Sinha, et al. AE9C90CB: a novel, bladder-selective muscarinic receptor antagonist for the treatment of overactive bladder. Comparative Study Br J Pharmacol. 2010 Jul;160 (5) :1119-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR1; mAChR2; mAChR3; mAChR4; mAChR5
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