CTB (Standard)
CTB (Standard) is the analytical standard of CTB. This product is intended for research and analytical applications. CTB is a potent p300 histone acetyltransferase activator[1]. CTB can effectively induce apoptosis in MCF-7 cells[2].
Product Specifications
CAS Number
451491-47-7
UNSPSC
12352100
Target
Apoptosis; Histone Acetyltransferase; Reference Standards
Related Pathways
Apoptosis; Epigenetics; Others
Field of Research
Cancer; Neurological Disease
Smiles
O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=CC=CC=C2OCC
Molecular Formula
C16H13ClF3NO2
Molecular Weight
343.73
References & Citations
[1]Mantelingu K, et al. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy. J Phys Chem B. 2007;111 (17) :4527-4534. |[2]Chen X, et al. Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy. Mol Neurodegener. 2020;15 (1) :2. Published 2020 Jan 6.|[3]Dastjerdi MN, et al. The effect of CTB on P53 protein acetylation and consequence apoptosis on MCF-7 and MRC-5 cell lines. Adv Biomed Res. 2013;2:24. Published 2013 Mar 6.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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