CTB (Standard)

CTB (Standard) is the analytical standard of CTB. This product is intended for research and analytical applications. CTB is a potent p300 histone acetyltransferase activator[1]. CTB can effectively induce apoptosis in MCF-7 cells[2].

Product Specifications

CAS Number

[451491-47-7]

UNSPSC

12352100

Target

Apoptosis; Histone Acetyltransferase; Reference Standards

Related Pathways

Apoptosis; Epigenetics; Others

Field of Research

Cancer; Neurological Disease

Smiles

O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=CC=CC=C2OCC

Molecular Formula

C16H13ClF3NO2

Molecular Weight

343.73

References & Citations

[1]Mantelingu K, et al. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy. J Phys Chem B. 2007;111 (17) :4527-4534. |[2]Chen X, et al. Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy. Mol Neurodegener. 2020;15 (1) :2. Published 2020 Jan 6.|[3]Dastjerdi MN, et al. The effect of CTB on P53 protein acetylation and consequence apoptosis on MCF-7 and MRC-5 cell lines. Adv Biomed Res. 2013;2:24. Published 2013 Mar 6.