BC8-15
BC8-15 is a PDE inhibitor with IC50 values of 0.28, 0.22, and 6.46 µM for inhibiting PDE8A, PDE4A, and PDE7A, respectively. BC8-15 can enhance steroidogenesis in mouse Leydig cells[1].
Product Specifications
CAS Number
[950385-77-0]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(C1=CC(NC2=NC3=C(C4=NN=C(CC)N24)C=CC=C3)=CC=C1)O
Molecular Formula
C18H15N5O2
Molecular Weight
333.34
References & Citations
[1]Demirbas D, et al. A yeast-based chemical screen identifies a PDE inhibitor that elevates steroidogenesis in mouse Leydig cells via PDE8 and PDE4 inhibition[J]. PLoS One, 2013, 8 (8) : e71279.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134937/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4; PDE7; PDE8
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