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BC8-15

BC8-15 is a PDE inhibitor with IC50 values of 0.28, 0.22, and 6.46 µM for inhibiting PDE8A, PDE4A, and PDE7A, respectively. BC8-15 can enhance steroidogenesis in mouse Leydig cells[1].

Product Specifications

CAS Number

950385-77-0

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=C(C1=CC(NC2=NC3=C(C4=NN=C(CC)N24)C=CC=C3)=CC=C1)O

Molecular Formula

C18H15N5O2

Molecular Weight

333.34

References & Citations

[1]Demirbas D, et al. A yeast-based chemical screen identifies a PDE inhibitor that elevates steroidogenesis in mouse Leydig cells via PDE8 and PDE4 inhibition[J]. PLoS One, 2013, 8 (8) : e71279.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE4; PDE7; PDE8

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