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BMS-142

BMS-142 is a PDL1 inhibitor (IC50 = 96.7 nM) (kd = 13.2 nM) . BMS-142 can reduce the survival rate of acute T-lymphoblastic leukemia cells and ovarian cancer cells. BMS-142 can be used in research on cancers such as acute T-lymphoblastic leukemia and ovarian cancer[1].

Product Specifications

CAS Number

1675203-24-3

UNSPSC

12352005

Target

PD-1/PD-L1

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

N#CC1=C(COC2=CC(OC)=C(CNCCO)C(OC)=C2)C=CC=C1C3=CC=CC=C3

Molecular Formula

C25H26N2O4

Molecular Weight

418.48

References & Citations

[1]Ganesan A, et al. Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. Sci Rep. 2019 Aug 27;9 (1) :12392. d

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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