Avatrombopag (hydrochloride) (Standard)
Avatrombopag (hydrochloride) (Standard) is the analytical standard of Avatrombopag (hydrochloride) . This product is intended for research and analytical applications. Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM) . Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A[1][2][3].
Product Specifications
CAS Number
570403-17-7
UNSPSC
12352100
Target
Reference Standards; Thrombopoietin Receptor
Related Pathways
Immunology/Inflammation; Others
Field of Research
Cardiovascular Disease; Cancer
Smiles
O=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC(Cl)=CS4)=C(N5CCN(C6CCCCC6)CC5)S3)=O)C=C2Cl)CC1)O.Cl
Molecular Formula
C29H35Cl3N6O3S2
Molecular Weight
686.12
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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