Ac-VDVAD-CHO (TFA)
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor (IC50: 46 and 15 nM) [1].
Product Specifications
UNSPSC
12352209
Target
Caspase
Related Pathways
Apoptosis
Field of Research
Others
Purity
99.15
Smiles
CC(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C25H38F3N5O12
Molecular Weight
657.59
References & Citations
[1]Maillard MC, et al. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19 (19) :5833-51.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 2; Caspase 3
Available Sizes
Curated Selection
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