RJW103
RJW103 is a selective steroidogenic factor-1 (SF-1, NR5A1) agonist with a pEC50 of 6.5. RJW103 shows a pEC50 of 5.9 for liver receptor homologue-1 (LRH-1, NR5A2) . RJW103 can be used for the researches of cancer, endocrinology and metabolic disease, such as adrenal cortex neoplasms[1].
Product Specifications
CAS Number
1276664-14-2
UNSPSC
12352005
Target
Orphan Nuclear Receptor
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Endocrinology; Metabolic Disease
Smiles
C=C([C@]1(C(C2=CC=CC=C2)=C(CCCCCC)C3)[C@]3([H])CN(C)C1)C4=CC=CC=C4
Molecular Formula
C28H35N
Molecular Weight
385.58
References & Citations
[1]Whitby RJ, et al. Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2) . J Med Chem. 2011 Apr 14;54 (7) :2266-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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