RJW103

RJW103 is a selective steroidogenic factor-1 (SF-1, NR5A1) agonist with a pEC50 of 6.5. RJW103 shows a pEC50 of 5.9 for liver receptor homologue-1 (LRH-1, NR5A2) . RJW103 can be used for the researches of cancer, endocrinology and metabolic disease, such as adrenal cortex neoplasms[1].

Product Specifications

CAS Number

[1276664-14-2]

UNSPSC

12352005

Target

Orphan Nuclear Receptor

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Endocrinology; Metabolic Disease

Smiles

C=C([C@]1(C(C2=CC=CC=C2)=C(CCCCCC)C3)[C@]3([H])CN(C)C1)C4=CC=CC=C4

Molecular Formula

C28H35N

Molecular Weight

385.58

References & Citations

[1]Whitby RJ, et al. Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2) . J Med Chem. 2011 Apr 14;54 (7) :2266-81.