Bis-Br-ANT-ATP (tetrasodium)

Bis-Br-ANT-ATP (tetrasodium) is a fluorescent derivative of adenosine-5’-triphosphate (ATP) (HY-B2176) . Bis-Br-ANT-ATP (tetrasodium) selectively inhibits B. pertussis adenylyl cyclase toxin CyaA (Ki: 12.6 nM) . Bis-Br-ANT-ATP (tetrasodium) can be used in Whooping cough research[1].

Product Specifications

UNSPSC

12352005

Target

Adenylate Cyclase; Bacterial

Related Pathways

Anti-infection; GPCR/G Protein

Field of Research

Infection

Smiles

NC(N=CN=C12)=C1N=CN2[C@@H]3O[C@H](COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)[C@@H](OC(C4=C(C=CC(Br)=C4)N)=O)[C@H]3OC(C5=C(C=CC(Br)=C5)N)=O

Molecular Formula

C24H20Br2N7Na4O15P3

Molecular Weight

991.14

References & Citations

[1]Geduhn J, et al. Bis-halogen-anthraniloyl-substituted nucleoside 5'-triphosphates as potent and selective inhibitors of Bordetella pertussis adenylyl cyclase toxin. J Pharmacol Exp Ther. 2011 Jan;336 (1) :104-15.