Ionomycin (calcium) (Standard)

2- (1-Piperazinyl) pyrimidine (Standard) is the analytical standard of 2- (1-Piperazinyl) pyrimidine. This product is intended for research and analytical applications. 2- (1-Piperazinyl) pyrimidine is the major metabolite of Tandospirone (HY-14558) [1].

Product Specifications

CAS Number

[56092-82-1]

Product Name Alternative

SQ23377 (calcium) (Standard)

UNSPSC

12352005

Target

Antibiotic; Apoptosis; Bacterial; Calcium Channel; PKC; Reference Standards

Related Pathways

Anti-infection; Apoptosis; Epigenetics; Membrane Transporter/Ion Channel; Neuronal Signaling; Others; TGF-beta/Smad

Field of Research

Cancer; Infection

Smiles

O=C([O-])CC[C@@H](C)C[C@H](C)C[C@H](C)C(/C=C([O-])/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@]([C@@H]2O[C@](C)([C@H](O)C)CC2)(C)O1)=O.[Ca+2]

Molecular Formula

C41H70CaO9

Molecular Weight

747.07

References & Citations

[1]Liu C, et al. Characterization of ionomycin as a calcium ionophore. J Biol Chem. 1978 Sep 10;253 (17) :5892-4.|[2]Chatila T, et al. Mechanisms of T cell activation by the calcium ionophore ionomycin. J Immunol. 1989 Aug 15;143 (4) :1283-9.|[3]Gil-Parrado S, et al. Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members. J Biol Chem. 2002 Jul 26;277 (30) :27217-26.|[4]Stoeck A, et al A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44. Biochem J. 2006 Feb 1;393 (Pt 3) :609-18.