8-NH2-ATP (tetrasodium)

8-NH2-ATP tetrasodium, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado tetrasodium induces apoptosis-related cleavage of poly (ADP-ribose) polymerase[1][2].

Product Specifications

CAS Number

[35892-97-8]

Product Name Alternative

8-Aminoadenosine-5'-O-triphosphate (tetrasodium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Concentration

10 mM * 163.90 μL in Water

Purity

98.0

Solubility

10 mM in DMSO

Smiles

NC(N([C@]([C@@H]([C@@H]1O)O)([H])O[C@@H]1CO[P](O[P](O[P](O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)C2=NC=N3)=NC2=C3N

Molecular Formula

C10H13N6Na4O13P3

Molecular Weight

610.12

References & Citations

[1]Nancy L Krett, et al. 8-amino-adenosine is a potential therapeutic agent for multiple myeloma. Mol Cancer Ther. 2004 Nov;3 (11) :1411-20.|[2]Yuji Matsuzaki, et al. ATP-association to intrabacterial nanotransportation system in Vibrio cholera. Med Mol Morphol. 2015 Dec;48 (4) :225-34.