8-Bromoinosine-5'-O-triphosphate (tetrasodium)

8-Bromoinosine-5'-O-triphosphate (8-Br-ITP) tetrasodium is a derivative of the nucleoside triphosphate Inosine-5'-triphosphate (ITP) (HY-W013706) . 8-Bromoinosine-5'-O-triphosphate tetrasodium can be used in the determination of nucleoside diphosphate kinase (NDPK) activity[1].

Product Specifications

Product Name Alternative

8-Br-ITP (tetrasodium) ; 8-Bromo ITP (tetrasodium)

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Smiles

O=C1C2=C(N([C@@H]3O[C@H](COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)[C@@H](O)[C@H]3O)C(Br)=N2)NC=N1

Molecular Formula

C10H10BrN4Na4O14P3

Molecular Weight

674.99

References & Citations

[1]Dautant A, et al. Hydrogen/Deuterium Exchange Mass Spectrometry Reveals Mechanistic Details of Activation of Nucleoside Diphosphate Kinases by Oligomerization. Biochemistry. 2017 Jun 13;56 (23) :2886-2896.