SR1001 (Standard)
SR1001 (Standard) is the analytical standard of SR1001. This product is intended for research and analytical applications. SR1001 is a selective RORα and RORγt inverse agonist with Kis 172 and 111 nM, respectively.
Product Specifications
CAS Number
1335106-03-0
UNSPSC
12352100
Target
Reference Standards; REV-ERB; ROR
Related Pathways
Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Smiles
CC(NC1=NC(C)=C(S(=O)(NC2=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C2)=O)S1)=O
Molecular Formula
C15H13F6N3O4S2
Molecular Weight
477.40
References & Citations
[1]Solt LA, et al. Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature. 2011 Apr 28;472 (7344) :491-4.|[2]Crumbley C, et al. Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor α (RORα) . PLoS One. 2012;7 (4) :e33804.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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