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SR1001 (Standard)

SR1001 (Standard) is the analytical standard of SR1001. This product is intended for research and analytical applications. SR1001 is a selective RORα and RORγt inverse agonist with Kis 172 and 111 nM, respectively.

Product Specifications

CAS Number

1335106-03-0

UNSPSC

12352100

Target

Reference Standards; REV-ERB; ROR

Related Pathways

Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Inflammation/Immunology

Smiles

CC(NC1=NC(C)=C(S(=O)(NC2=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C2)=O)S1)=O

Molecular Formula

C15H13F6N3O4S2

Molecular Weight

477.40

References & Citations

[1]Solt LA, et al. Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature. 2011 Apr 28;472 (7344) :491-4.|[2]Crumbley C, et al. Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor α (RORα) . PLoS One. 2012;7 (4) :e33804.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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