TH301
TH301 is a Phenylpyrazole derivative. TH301 selectively stabilize CRY2. TH301 dose-dependently prolongs circadian period[1].
Product Specifications
CAS Number
[450338-32-6]
UNSPSC
12352005
Target
Cryptochrome; Drug Derivative
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Smiles
O=C(C1(C2=CC=C(Cl)C=C2)CCCC1)NC3=C4C(CS(C4)(=O)=O)=NN3C5=CC=C(OC)C=C5
Molecular Formula
C24H24ClN3O4S
Molecular Weight
485.98
References & Citations
[1]Miller S, et al. Isoform-selective regulation of mammalian cryptochromes. Nat Chem Biol. 2020 Jun;16 (6) :676-685.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CRY2
Curated Selection
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