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Desmethylene tadalafil

Desmethylene tadalafil is a metabolite of Tadalafil. The formation of Desmethylene tadalafil mediated predominantly by CYP3A4[1].

Product Specifications

CAS Number

171489-03-5

UNSPSC

12352005

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Endocrinology; Neurological Disease; Cardiovascular Disease

Smiles

O=C([C@@]1([H])CC2=C([C@@H](C3=CC=C(O)C(O)=C3)N14)NC5=C2C=CC=C5)N(C)CC4=O

Molecular Formula

C21H19N3O4

Molecular Weight

377.39

References & Citations

[1]Yu J, et al. Cytochrome P450-mediated metabolic interactions between donepezil and tadalafil in human liver microsomes. Toxicol In Vitro. 2024 Oct;100:105922.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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