Desmethylene tadalafil
Desmethylene tadalafil is a metabolite of Tadalafil. The formation of Desmethylene tadalafil mediated predominantly by CYP3A4[1].
Product Specifications
CAS Number
171489-03-5
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology; Neurological Disease; Cardiovascular Disease
Smiles
O=C([C@@]1([H])CC2=C([C@@H](C3=CC=C(O)C(O)=C3)N14)NC5=C2C=CC=C5)N(C)CC4=O
Molecular Formula
C21H19N3O4
Molecular Weight
377.39
References & Citations
[1]Yu J, et al. Cytochrome P450-mediated metabolic interactions between donepezil and tadalafil in human liver microsomes. Toxicol In Vitro. 2024 Oct;100:105922.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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