CIL-102
CIL-102, an apoptosis inducer, is a MMP-2/MMP-9 inhibitor that decreases MMP-2/MMP-9 protein expression and mRNA levels. CIL-102 displays an anti-cancer activity[1].
Product Specifications
CAS Number
[479077-76-4]
UNSPSC
12352005
Target
Apoptosis; MMP
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
CC(C1=CC=C(NC2=C3C(OC=C3)=NC4=CC=CC=C24)C=C1)=O
Molecular Formula
C19H14N2O2
Molecular Weight
302.33
References & Citations
[1]Liu WH, et al. CIL-102 induces matrix metalloproteinase-2 (MMP-2) /MMP-9 down-regulation via simultaneous suppression of genetic transcription and mRNA stability. Int J Biochem Cell Biol. 2012 Dec;44 (12) :2212-22.|[2]Huang WS, et al. CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45. PLoS One. 2017 Jan 9;12 (1) :e0168989.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-133845/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-2; MMP-9
Curated Selection
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