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I-AZD1775 (TFA)

I-AZD1775 (TFA) is an immobilizable analogue of AZD1775. i-AZD1775 (TFA) retains the ability to inhibit WEE1 in vitro. i-AZD1775 (TFA) can be studied in anticancer research[1].

Product Specifications

CAS Number

2858813-30-4

UNSPSC

12352005

Target

Wee1

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C(C(F)(F)F)O.O=C1C2=CN=C(NC3=CC=C(N4CCN(CCCN)CC4)C=C3)N=C2N(N1CC=C)C5=CC=CC(C(C)(C)O)=N5

Molecular Formula

C31H38F3N9O4

Molecular Weight

657.69

References & Citations

[1]Wright, G., et al., (2017) . Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity. ACS chemical biology, 12 (7), 1883–1892.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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