Tert-Butyl 8-hydroxyoctanoate
Tert-Butyl 8-hydroxyoctanoate is a PROTAC linker that can be used for the synthesis of PROTACs, such as PROTAC CDK Degrader-1 (HY-133617) . PROTAC CDK Degrader-1 is a potent CDK PROTAC degrader with anti-tumor activity[1].
Product Specifications
CAS Number
[401901-41-5]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Cancer
Purity
99.46
Smiles
O=C(OC(C)(C)C)CCCCCCCO
Molecular Formula
C12H24O3
Molecular Weight
216.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Chenxiaohua, et al. Degradation agents for cyclin dependent kinase, preparation method therefor, pharmaceutical composition thereof and use thereof. WO2020035049.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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