1,1,3-Tribromoacetone (Standard)
1,1,3-Tribromoacetone (Standard) is the analytical standard of 1,1,3-Tribromoacetone. This product is intended for research and analytical applications. 1,1,3-Tribromoacetone is an impurity of Methotrexate. Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis[1].
Product Specifications
CAS Number
3475-39-6
UNSPSC
12352211
Target
Drug Metabolite; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C(CBr)C(Br)Br
Molecular Formula
C3H3Br3O
Molecular Weight
294.77
References & Citations
[1]Balwant Singh, et al. Process for the preparation of high purity methotrexate and derivatives thereof. Patent US4374987A 87A|[2][2].Swierkot J, et al. Methotrexate in rheumatoid arthritis. Pharmacol Rep. 2006 Jul-Aug;58 (4) :473-92|[3]Banji D, et al. Evaluation of the concomitant use of methotrexate and curcumin on Freund's complete adjuvant-induced arthritis and hematological indices in rats. Indian J Pharmacol. 2011;43 (5) :546-550.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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