Mabuterol (Standard)
Mabuterol (Standard) is the analytical standard of Mabuterol. This product is intended for research and analytical applications. Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB[1][2].
Product Specifications
CAS Number
56341-08-3
UNSPSC
12352100
Target
Adrenergic Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease
Smiles
CC(NCC(O)C1=CC(C(F)(F)F)=C(N)C(Cl)=C1)(C)C
Molecular Formula
C13H18ClF3N2O
Molecular Weight
310.74
References & Citations
[1]Yamamoto I, et al. Enzyme immunoassay for mabuterol, a selective beta 2-adrenergic stimulant in the trachea. J Immunoassay. 1985;6 (3) :261-76. |[2]Yaru Gu, et al. Inhibitory effect of mabuterol on proliferation of rat ASMCs induced by PDGF-BB via regulating [Ca2+]i and mitochondrial fission/fusion. Interactions, 2019, 307: 63-72.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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