Sapanisertib (Standard)
Sapanisertib (Standard) is the analytical standard of Sapanisertib. This product is intended for research and analytical applications. Sapanisertib (INK-128; MLN0128; TAK-228) is an orally available, ATP-dependent mTOR1/2 inhibitor with an IC50 of 1 nM for mTOR kinase.
Product Specifications
CAS Number
1224844-38-5
UNSPSC
12352100
Target
Autophagy; mTOR; Reference Standards
Related Pathways
Autophagy; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
NC1=NC=NC2=C1C(C3=CC4=C(C=C3)OC(N)=N4)=NN2C(C)C
Molecular Formula
C15H15N7O
Molecular Weight
309.33
References & Citations
[1]Liu A, et al. mTOR Mediated Anti-Cancer Drug Discovery. Drug Discovery Today: Therapeutic Strategies. 2009, 6 (2), 47-55.|[2]Hsieh AC, et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 2012 Feb 22;485 (7396) :55-61.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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