MS-153

MS-153 is a glutamate transporter activator that can be used as a neuroprotective agent[1][2].

Product Specifications

CAS Number

[130775-79-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H320-H335

Target

EAAT

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Smiles

C[C@@H]1CC=NN1C(C2=CN=CC=C2)=O

Molecular Formula

C10H11N3O

Molecular Weight

189.21

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Shimada F, et al. The neuroprotective agent MS-153 stimulates glutamate uptake. Eur J Pharmacol. 1999 Dec 15;386 (2-3) :263-70.|[2]Nakagawa T, et al. Inhibition of morphine tolerance and dependence by MS-153, a glutamate transporter activator. Eur J Pharmacol. 2001 May 4;419 (1) :39-45.