(R) -Norfluoxetine

(R) -Norfluoxetine is the (R) -enantiomer of Norfluoxetine (HY-135556) . (R) -Norfluoxetine is a potent serotonin re-uptake inhibitor, with a Ki of 13 nM. (R) -Norfluoxetine can be used for the research of depression[1].

Product Specifications

CAS Number

[130194-43-3]

UNSPSC

12352005

Hazard Statement

H319

Target

Serotonin Transporter

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

FC(F)(F)C1=CC=C(O[C@H](CCN)C2=CC=CC=C2)C=C1

Molecular Formula

C16H16F3NO

Molecular Weight

295.30

Precautions

P264-P280-P305+P351+P338

References & Citations

[1]Cashman JR, et al. Stereoselective inhibition of serotonin re-uptake and phosphodiesterase by dual inhibitors as potential agents for depression. Bioorg Med Chem. 2009 Jan 1;17 (1) :337-43.