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Desmethyl Erlotinib (hydrochloride) (Standard)

Metoclopramide (hydrochloride hydrate) (Standard) is the analytical standard of Metoclopramide (hydrochloride hydrate) . This product is intended for research and analytical applications. Metoclopramide hydrochloride hydrate is a potent antagonist of 5-HT3 and dopamine D2 receptor, with IC50s of 308 nM and 483 nM, respectively. Metoclopramide hydrochloride hydrate can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis[1][2].

Product Specifications

CAS Number

183320-51-6

Product Name Alternative

OSI-420 (Standard) ; CP-373420 (hydrochloride) (Standard)

UNSPSC

12352005

Target

Drug Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

OCCOC1=CC2=C(N=CN=C2NC3=CC=CC(C#C)=C3)C=C1OCCOC.Cl

Molecular Formula

C21H22ClN3O4

Molecular Weight

415.87

References & Citations

[1]Thappali SR, et al. Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation.Sci Pharm. 2012 Jul-Sep;80 (3) :633-46.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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