Alvimopan-d7
Alvimopan-d7 (ADL 8-2698-d7) is deuterium labeled Alvimopan. Alvimopan (ADL 8-2698) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively) . Alvimopan can be used for the research of postoperative ileus[1][2][3].
Product Specifications
CAS Number
[1261396-48-8]
Product Name Alternative
ADL 8-2698-d7; LY 246736-d7
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cancer
Smiles
C[C@]1(C2=CC(O)=CC=C2)[C@H](CN(CC1)C[C@@H](C(NCC(O)=O)=O)C([2H])([2H])C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])C
Molecular Formula
C25H25D7N2O4
Molecular Weight
431.58
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13243S1/
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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