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(E/Z) -Rivanicline

(E/Z) -Rivanicline ((E/Z) -RJR-2403, (E/Z) -Metanicotine) is the E/Z mixture of Rivanicline (HY-13225A) . Rivanicline is a neuronal nicotinic receptor (neuronal nicotinic receptor) agonist that is highly selective for the α4β2 subtype, Ki is 26 nM, which is more than 1000 times more inhibitory than α7 receptor[1].

Product Specifications

CAS Number

[538-79-4]

Product Name Alternative

(E/Z) -RJR-2403; (E/Z) -Metanicotine

UNSPSC

12352005

Target

NAChR

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

CNCC/C=C/C1=CC=CN=C1

Molecular Formula

C10H14N2

Molecular Weight

162.23

References & Citations

[1]Luanratana O, et al. Alkaloids of Duboisia hopwoodii[J]. Phytochemistry, 1982, 21 (2) : 449-451.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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