Vanoxerine (dihydrochloride) (Standard)
Vanoxerine (dihydrochloride) (Standard) is the analytical standard of Vanoxerine (dihydrochloride) . This product is intended for research and analytical applications. Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM) . Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) binds to the target site on the dopamine transporter (DAT) [1].
Product Specifications
CAS Number
67469-78-7
UNSPSC
12352100
Target
Dopamine Transporter; Reference Standards
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
FC1=CC=C(C(C2=CC=C(F)C=C2)OCCN3CCN(CCCC4=CC=CC=C4)CC3)C=C1.[2HCl]
Molecular Formula
C28H34Cl2F2N2O
Molecular Weight
523.49
References & Citations
[1]Rothman RB, et al. Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction. Biochem Pharmacol. 2008 Jan 1;75 (1) :2-16.|[2]Andersen PH. The dopamine inhibitor GBR 12909: selectivity and molecular mechanism of action. Eur J Pharmacol.|[3]Hirate K, et al. Characteristics of the ambulation-increasing effect of GBR-12909, a selective dopamine uptakeinhibitor, in mice. Jpn J Pharmacol. 1991 Apr;55 (4) :501-11.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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