Gly-7-MAD-MDCPT (TFA)
Gly-7-MAD-MDCPT (Compound 4b) TFA is an anticancer agent. Gly-7-MAD-MDCPT TFA is a Camptothecin (HY-16560) compound, which shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM[1].
Product Specifications
UNSPSC
12352203
Target
ADC Payload; Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
95.15
Smiles
NCC(NCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O.O=C(O)C(F)(F)F
Molecular Formula
C26H23F3N4O9
Molecular Weight
592.48
References & Citations
[1]Jeffrey Scott, et al. Preparation of camptothecin peptide conjugates as antitumor agents. WO2019195665. 2019 10-10.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132164B/
Scientific Category
ADC Related
Clinical Information
No Development Reported
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