Lysoganglioside-GM1 (ammonium)
Lysoganglioside-GM1 (LysoGM1) ammonium is a derivative of Monosialoganglioside GM1, which lacks a fatty acid. Lysoganglioside-GM1 ammonium is also an inhibitor of GM1 aggregation. Lysoganglioside-GM1 ammonium can inhibit the activation of Lyn and laminin-1-mediated neurite outgrowth. Lysoganglioside-GM1 ammonium can be used in the research of nervous system diseases[1].
Product Specifications
Product Name Alternative
LysoGM1 (ammonium)
UNSPSC
12352211
Target
Src
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Smiles
OC([C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)O[C@H]2[C@H]([C@H](O[C@H]([C@@H]2O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCCCC)CO)CO)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O[C@@H]5O[C@@H]([C@@H]([C@@H]([C@H]5O)O)O)CO)NC(C)=O)=O.[NH4]
Molecular Formula
C55H101N4O30
Molecular Weight
1298.40
References & Citations
[1]Ichikawa N, et al. Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth. J Cell Sci. 2009 Jan 15;122 (Pt 2) :289-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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