Lysoganglioside-GM1 (ammonium)

Lysoganglioside-GM1 (LysoGM1) ammonium is a derivative of Monosialoganglioside GM1, which lacks a fatty acid. Lysoganglioside-GM1 ammonium is also an inhibitor of GM1 aggregation. Lysoganglioside-GM1 ammonium can inhibit the activation of Lyn and laminin-1-mediated neurite outgrowth. Lysoganglioside-GM1 ammonium can be used in the research of nervous system diseases[1].

Product Specifications

Product Name Alternative

LysoGM1 (ammonium)

UNSPSC

12352211

Target

Src

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Neurological Disease

Smiles

OC([C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)O[C@H]2[C@H]([C@H](O[C@H]([C@@H]2O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCCCC)CO)CO)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O[C@@H]5O[C@@H]([C@@H]([C@@H]([C@H]5O)O)O)CO)NC(C)=O)=O.[NH4]

Molecular Formula

C55H101N4O30

Molecular Weight

1298.40

References & Citations

[1]Ichikawa N, et al. Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth. J Cell Sci. 2009 Jan 15;122 (Pt 2) :289-99.