Iso-OMPA (Standard)

Iso-OMPA (Standard) is the analytical standard of Iso-OMPA. This product is intended for research and analytical applications. Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE) . Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE) [1][2][3].

Product Specifications

CAS Number

513-00-8

UNSPSC

12352100

Target

Cholinesterase (ChE) ; Reference Standards

Related Pathways

Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

O=P(NC(C)C)(NC(C)C)OP(NC(C)C)(NC(C)C)=O

Molecular Formula

C12H32N4O3P2

Molecular Weight

342.36

References & Citations

[1]Rodríguez-Fuentes G, et al. Characterization of cholinesterase activity from different tissues of Nile tilapia (Oreochromis niloticus) . Mar Environ Res. 2004 Aug-Dec;58 (2-5) :505-9.|[2]Z Grubic, et al. Iso-OMPA-induced potentiation of soman toxicity in rat correlates with the inhibition of plasma carboxylesterases. Arch Toxicol. 1988;62 (5) :398-9.|[3]X Norel, et al. Degradation of acetylcholine in human airways: role of butyrylcholinesterase. Br J Pharmacol. 1993 Apr;108 (4) :914-9.