Protein kinase inhibitor H-7 (Standard)

Protein kinase inhibitor H-7 (Standard) is the analytical standard of Protein kinase inhibitor H-7. This product is intended for research and analytical applications. Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) and cyclic nucleotide dependent protein kinase, with a Ki of 6 μM for PKC[1].

Product Specifications

CAS Number

[84477-87-2]

UNSPSC

12352100

Target

PKC; Reference Standards

Related Pathways

Epigenetics; Others; TGF-beta/Smad

Field of Research

Cancer

Smiles

O=S(C1=CC=CC2=C1C=CN=C2)(N3C(C)CNCC3)=O

Molecular Formula

C14H17N3O2S

Molecular Weight

291.38

References & Citations

[1]Hidaka H, et, al. Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry. 1984 Oct 9;23 (21) :5036-41.