FR144420
FR144420 (NOR4) is an orally active nitric oxide (NO) -releasing agent with vasodilatory and antiplatelet effects. FR144420 induces cGMP-mediated vasodilation and inhibits platelet aggregation. FR144420 is promising for research of cardiovascular diseases, particularly angina pectoris and coronary artery spasm[1].
Product Specifications
CAS Number
162626-99-5
Product Name Alternative
NOR4
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
NO Synthase
Related Pathways
Immunology/Inflammation
Field of Research
Cardiovascular Disease
Smiles
O=C(C1=CC=CN=C1)NCC(/C=C(CC)/C([N+]([O-])=O)C)=N\O
Molecular Formula
C14H18N4O4
Molecular Weight
306.32
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Hirasawa Y, et al. Antianginal effects of FR144420, a novel slow nitric oxide-releasing agent. Eur J Pharmacol. 1996 May 6;303 (1-2) :55-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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