6-Bn-ADP (sodium)

6-Bn-ADP (N6-benzyl ADP) sodium is a derivative of Adenosine 5'-diphosphate (ADP) (HY-W010918) that inhibits ATP hydrolysis. 6-Bn-ADP sodium inhibits the ATPase activities of Mortalin, Hsc70, and Hsp70 protein with Kis of 86.51 μM, 294.5 μM, and 1612 μM, respectively[1].

Product Specifications

Product Name Alternative

N6-benzyl ADP (sodium)

UNSPSC

12352005

Target

ATP Synthase

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(NCC4=CC=CC=C4)=C3N=C2)O[C@@H]1COP(OP(O[Na])(O[Na])=O)(O[Na])=O

Molecular Formula

C17H18N5Na3O10P2

Molecular Weight

583.27

References & Citations

[1]Moseng MA, et al. 2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin. FEBS Lett. 2019 Aug;593 (15) :2030-2039.