3'-NH2-ATP (tetrasodium)

3'-NH2-ATP tetrasodium is an ATP substitute created by inserting an amino acid at the C3 position of ATP. 3'-NH2-ATP tetrasodium catalyzes RNA synthesis in the presence of RNA polymerase[1].

Product Specifications

UNSPSC

12352200

Target

Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Smiles

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](N)[C@@H](COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)O3

Molecular Formula

C10H13N6Na4O12P3

Molecular Weight

594.12

References & Citations

[1]Kutateladze T, et al. 3'-deoxy-3'-aminonucleoside 5'-triphosphates--terminators of RNA synthesis, catalyzed by DNA-dependent RNA polymerase from Escherichia coli. FEBS Lett. 1983 Mar 21;153 (2) :420-6.