3'-Amino-3'-deoxyadenosine-5'-O-diphosphate (sodium)

3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium is an amine-modified nucleotide that can be used in the synthesis of other active compounds. The coumarin-labeled derivatives of 3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium exhibit significant fluorescence changes when interacting with myosin and can mimic the function of natural ADP[1][2].

Product Specifications

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Smiles

O[C@@H]1[C@H](N)[C@@H](COP(OP(O[Na])(O[Na])=O)(O[Na])=O)O[C@H]1N2C3=NC=NC(N)=C3N=C2

Molecular Formula

C10H13N6Na3O9P2

Molecular Weight

492.16

References & Citations

[1]Mojr V, et al. Nonhydrolysable Analogues of (p) ppGpp and (p) ppApp Alarmone Nucleotides as Novel Molecular Tools. ACS Chem Biol. 2021 Sep 17;16 (9) :1680-1691.|[2]Webb MR, et al. A series of related nucleotide analogues that aids optimization of fluorescence signals in probing the mechanism of P-loop ATPases, such as actomyosin. Biochemistry. 2004 Nov 16;43 (45) :14463-71.