Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ganglioside GT1b (porcine) (ammonium)

Selected Variant

HY-131686A-01

Size: 1 mg

Ganglioside GT1b (porcine) ammonium is a member of the ganglioside family. Ganglioside GT1b (porcine) ammonium acts as a protective signal against nerve injury-induced spinal synapse elimination. Ganglioside GT1b (porcine) ammonium induces HA synthesis and the phosphorylation of Akt/mTOR in orbital fibroblasts. Ganglioside GT1b (porcine) ammonium enhances porcine oocyte maturation and induces activation of EGFR and ERK1/2 signaling. Ganglioside GT1b (porcine) ammonium is a putative host cell receptor for the Merkel cell polyomavirus. Ganglioside GT1b (porcine) ammonium can be used for the researches of cancer, infection, immunology, endocrinology and neurological disease, such as Thyroid eye disease[1][2][3][4].

Product Specifications

CAS Number

59247-13-1

UNSPSC

12352005

Target

Akt; EGFR; ERK; mTOR

Related Pathways

JAK/STAT Signaling; MAPK/ERK Pathway; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Field of Research

Cancer; Infection; Inflammation/Immunology; Metabolic Disease; Neurological Disease

Purity

98

Smiles

O[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[Ceramide])CO)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O[C@]5(C(O)=O)C[C@@H]([C@H]([C@@H](O5)[C@H](O)[C@H](O)CO)NC(C)=O)O)O)O)CO)O[C@]6(C(O)=O)C[C@@H]([C@H]([C@@H](O6)[C@H](O)[C@H](O[C@]7(C(O)=O)C[C@@H]([C@H]([C@@H](O7)[C@H](O)[C@H](O)CO)NC(C)=O)O)CO)NC(C)=O)O)O)O.N.N.N

References & Citations

[1]Lee J, et al. Ganglioside GT1b prevents selective spinal synapse removal following peripheral nerve injury. EMBO Rep. 2025 Jun;26 (12) :2994-3023. |[2]Yoo HK, et al. Ganglioside GT1b increases hyaluronic acid synthase 2 via PI3K activation with TLR2 dependence in orbital fibroblasts from thyroid eye disease patients. BMB Rep. 2021 Feb;54 (2) :136-141.|[3]Kim JW, et al. Exogenous Ganglioside GT1b Enhances Porcine Oocyte Maturation, Including the Cumulus Cell Expansion and Activation of EGFR and ERK1/2 Signaling. Reprod Sci. 2020 Jan;27 (1) :278-289. |[4]Erickson KD, et al. Ganglioside GT1b is a putative host cell receptor for the Merkel cell polyomavirus. J Virol. 2009 Oct;83 (19) :10275-9.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

GFAP (GA-5 + ASTRO/789), CF640R conjugate, 0.1mg/mL
BNC400898-100 1x 100 µL

GFAP (GA-5 + ASTRO/789), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Prostate Specific Acid Phosphatase (PSAP) (rACPP/1338), CF647 conjugate, 0.1mg/mL
BNC472074-100 1x 100 µL

Prostate Specific Acid Phosphatase (PSAP) (rACPP/1338), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Human IgM Immunoglobulin (ICO-30), 0.2mg/mL
BNUB0364-500 1x 500 µL

Human IgM Immunoglobulin (ICO-30), 0.2mg/mL

Sign In for Pricing
View Details
Anti-c-Fos Antibody Picoband®, Cy3 Conjugate
PA1318-Cy3 100 µg/Vial

Anti-c-Fos Antibody Picoband®, Cy3 Conjugate

Sign In for Pricing
View Details
TCL1 (T-Cell Marker) (TCL1/2747R), CF488A conjugate, 0.1mg/mL
BNC882747-500 1x 500 µL

TCL1 (T-Cell Marker) (TCL1/2747R), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD33 (C33/69), CF568 conjugate, 0.1mg/mL
BNC680069-100 1x 100 µL

CD33 (C33/69), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details